L-Glutamine

The gut lining of endurance runners breaks down under sustained training load; L-glutamine provides the primary substrate for intestinal cell repair, directly addressing the GI distress that derails training blocks and race days.

L-glutamine is the most abundant amino acid in the body and the principal fuel source for intestinal epithelial cells. Prolonged running lowers plasma glutamine levels and increases intestinal permeability, the mechanism behind runner's stomach, post-run GI distress, and elevated infection risk during heavy mileage. Supplementing with 3.15g daily supports gut barrier repair, immune function, and muscle tissue maintenance during high-volume training cycles.

Built for marathon and ultra runners who experience GI distress during or after long runs, runners in high-mileage training blocks where immune suppression is a recurring problem, and anyone managing the gut integrity issues that come with sustained endurance training. Pairs especially well with colostrum for runners dealing with persistent runner's stomach.

This supplement prioritizes a straightforward approach by focusing on a single high-quality active ingredient. By eliminating complex fillers, the formula remains minimalist and functional for those who value transparency in their supplementation. The inclusion of precise scoop (5cc / 3.3g) ensures you get the exact amount needed for your daily routine without any guesswork. It’s a reliable choice for anyone looking to streamline their nutritional intake while maintaining a busy, active lifestyle.*

How to Use

1. Post-run (daily maintenance): Mix one scoop (3.15g) into 6 - 8 oz of water or add to your post-run shake. Consistency matters more than timing - daily use over 3 to 4 weeks produces the most measurable gut and immune response.
2. High-mileage weeks: Take within 30 minutes of finishing runs exceeding 90 minutes, when plasma glutamine depletion is highest.
3. Stack: Pairs with Colostrum as a combined gut integrity protocol - L-glutamine provides the direct cellular substrate; colostrum supplies the immunoglobulins and growth factors that support barrier function from a different pathway.
4. Mix note: Unflavored. Dissolves in water, juice, or protein shakes without affecting taste.

Ingredients: L-Glutamine (3.15g), Silicon Dioxide.

Manufacturer's country: USA

Product amount (oz/lbs/g): 3.5 oz / 0.2 lbs / 98g

Gross weight (oz/lbs/g): 4.9 oz / 0.3 lbs / 139g

Suggested use: As a dietary supplement, adults mix one (1) scoop with 6-8 oz (177-237ml) of water or favorite beverage daily.

CAUTION: Do not exceed recommended dose. Pregnant or nursing mothers, children under the age of 18, and individuals with known medical conditions should consult a physician before using this or any dietary supplement.

KEEP OUT OF THE REACH OF CHILDREN. DO NOT USE IF SAFETY SEAL IS DAMAGED OR MISSING. STORE IN A COOL, DRY PLACE.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

FAQ

Q: Does L-glutamine actually help with runner's stomach?

A: Runner's stomach is partly driven by exercise-induced intestinal permeability - the gut lining loosens under endurance training stress, allowing bacteria and undigested particles into the bloodstream. L-glutamine is the primary fuel for the cells that maintain the gut barrier. At 3-10g daily, supplementation supports intestinal cell repair and reduces permeability markers. It works best as a daily protocol rather than a race-day intervention; allow 3-4 weeks of consistent use before assessing results.

Q: When should a runner take L-glutamine, and what dose is supported by research?

A: 3-10g daily is the range used in most endurance and gut-health research; this product delivers 3.15g per scoop. Post-run timing is preferred because plasma glutamine drops significantly after prolonged exercise, and the gut is most receptive to repair substrate in the hour following a hard effort. Runners in particularly high-mileage blocks (over 70 miles per week) may benefit from two servings daily - one post-run and one before sleep.

Q: Can female runners specifically benefit from L-glutamine?

A: Yes. Female runners managing high training loads alongside hormonal fluctuations face compounding immune suppression risk. L-glutamine supports both gut integrity and immune cell production - two systems under particular strain during heavy training. It stacks logically with colostrum and magnesium as part of a recovery protocol, particularly during marathon build phases or the two weeks following a goal race.

Q: Is L-glutamine useful beyond gut health - does it help with muscle recovery?

A: L-glutamine contributes to muscle recovery indirectly. It serves as a nitrogen shuttle in protein metabolism and helps preserve muscle glycogen following long efforts. However, its primary evidence base for runners is gut integrity and immune support, not direct muscle repair - for which protein (20-30g post-run) remains the more established intervention. Do not expect L-glutamine to replace protein; treat it as a gut and immune layer within a broader recovery stack.